2011-01-21

[DIV28SUPER] NIDA Neuroscience Update, January 21, 2011

Table of Contents

I.                    The Study of Tobacco in Minority Populations (STOMP) Genetics Consortium Seeks Additional Collaborators for meta-analyses of GWAS data for smoking behavior among African-Americans

II.                  RFA-DA-11-012  Exploring Human Induced Pluripotent Stem Cells for Substance Abuse Research (R21)

III.                PAR-11-099    U.S. - India Bilateral Brain Research Collaborative Partnerships (U.S. - India BRCP) (R21)

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I.                    The Study of Tobacco in Minority Populations (STOMP) Genetics Consortium Seeks Additional Collaborators for meta-analyses of GWAS data for smoking behavior among African-Americans.

The Study of Tobacco in Minority Populations (STOMP) Genetics Consortium was formed in early 2010 and consists of multiple investigators from different studies interested in conducting meta-analyses of GWAS data for smoking behavior among African-Americans. As of November 2010, n=27,072 African-American participants with GWAS and smoking data are available for analyses. The sample size represents participants from the Women's Health Initiative, the CARe studies and multiple NCI breast and prostate cancer studies. We are investigating smoking initiation (ever vs. never and age at onset of smoking), smoking heaviness (CPD) and smoking cessation (former vs. current smokers); have devised a standard analytic plan; and ask that new studies upload summary results to the MIT/Broad Shared Space. The STOMP Genetics Consortium analysts will conduct the meta-analyses. The Study of Tobacco in Minority Populations (STOMP) Genetics are actively recruiting more studies. Investigators interested in collaborating should contact Stacey Petruzella (petruzes@mskcc.org) for more information.

 

II.                  RFA-DA-11-012  Exploring Human Induced Pluripotent Stem Cells for Substance Abuse Research (R21)

Participating NIH Institute: NIDA

Letter of Intent: February 28, 2011

Receipt date: March 31, 2011, by 5:00 PM local time of applicant organization.

Purpose:  This FOA solicits applications to develop and standardize methods to generate cell types relevant to substance abuse from human iPS cells.  Cells of interest include neurons and glial cells, and cells of other tissues, if justification and rationale are provided.  The development of standardized approaches to reprogram or induce adult cells to become pluripotent stem cells will inform our understanding of the pathophysiology of substance use and abuse and may provide a novel mechanism for screening compounds for the treatment of addiction. 

III.                PAR-11-099    U.S. - India Bilateral Brain Research Collaborative Partnerships (U.S. - India BRCP) (R21)

 

Participating NIH Institutes: NINDS, NIMH and NIDA

Participating Indian Agency: Department of Biotechnology (DBT)

 

Letter of Intent Due Date:  Feb 22, 2011

Application Due date: March 22, 2011

 

Purpose: The purpose of this program is to support the establishment and enhancement of bilateral research collaborations between U.S. and Indian investigators in the field of neuroscience with an emphasis on understanding, treating and curing neurological, mental and addictive disorders. Specific areas of research may include, but are not limited to, studies of mechanisms underlying neurological, mental and addictive disorders and diseases, planning for population-based research and clinical trials, the development of infrastructures for resource, tool and data sharing in addition to projects aimed at advancing global health research, particularly as it relates to the mission of the participating organizations.

 

 

The National Institute on Drug Abuse at the National Institutes of Health is an agency of the United States Department of Health and Human Services

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